Rutgers, the State University of New Jersey

Other

University of Michigan

University of California

The University of Arizona

Bioresources International Inc.

Agricultural Research Organization Ministry of Agriculture and Rural Development

James E Simon

William Reichert

Thomas Villani

Adolfina Koroch

Qingli Wu

Eran Pichersky

Yoko Iijima

Efraim Lewinsohn

David R Gang

Stephen B Rhodes

Rong Di

Mingfu Wang

Kodzo Gbewonyo

Mohamed M Rafi

Qing-li Wu

Wenbin Deng

Daniel Fahene Acquaye

Yaw Asianowa

Cara Welch

Michael A Lawton

Robert Michael Pyne

Christain Andrew Wyenandt

The disclosure provides methods of making gene-edited plants that are resistant to downy mildew, such as plants with reduced expression of homoserine kinase (HSK), 2-oxoglutarate-Fe(II) oxygenase (2OGO), or both. The disclosure further provides methods of making gene-edited modified plants that are cold tolerant, such as plants with reduced expression of MYB14. In some examples, CRISPR/Cas methods are used, wherein the plants include a mutated HSK, 2OGO, and/or MYB14 gene resulting in reduced expression and/or gene activity. Plants generated using the methods are provided. Such plants can include other desirable traits. HSK, 2OGO, and/or MYB14 nucleic acid and protein molecules are provided, as are gRNAs specific for HSK, 2OGO, or MYB14 and vectors containing such.

Gene-edited basil plants resistant to downy mildew

The invention provides seed and plants of catnip hybrid 'CR9'. The invention thus relates to the plants, seeds, and tissue cultures of catnip hybrid 'CR9', and to methods for producing a catnip plant of the present invention by crossing such plants with themselves or with another catnip plant, such as a plant of another genotype, variety, or cultivar. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants.

Catnip cultivar 'CR9'

A new and distinctplant named 'Eli' is disclosed, which is characterized by dark green leaves, highly aromatic properties, high carvacrol with white flowers that appear and flower late in the season and about 14 weeks to maturity.

Oregano plant named 'Eli'

A new and distinctplant named 'Pierre' is disclosed, characterized by very high essential oil content, high carvacrol content, no flowering, broad plant width, and about 16 weeks to maturity.

Oregano plant named 'Pierre'

The disclosure provides seed, tissue cultures, essential oil extracts, and plants of catnip hybrid 'CR3', as well as methods for producing a catnip plants by crossing 'CR3'plants with themselves or with another catnip plant, such as a plant of another genotype, variety, or cultivar. The disclosure further provides seed, tissue cultures, essential oil extracts, and plants produced by such crossing. Methods of using the plants and extracts as insect repellents and in pet toys, are also provided.

Catnip cultivar 'CR3'

A clearing agent and mounting solution for microscopy is disclosed comprising at least trichloroethanol and/or derivatives thereof, where the refractive index of the solution is greater than or equal to about 1.3810. Also disclosed are methods of preparing specimens for microscopy.

Clearing agent and mounting media for microscopy

The disclosure provides seed, tissue cultures, essential oil extracts, and plants of catnip hybrid 'CR3', as well as methods for producing a catnip plants by crossing 'CR3' plants with themselves or with another catnip plant, such as a plant of another genotype, variety, or cultivar. The disclosure further provides seed, tissue cultures, essential oil extracts, and plants produced by such crossing. Methods of using the plants and extracts as insect repellents and in pet toys, are also provided.

Eight new sweet basil (L.) cultivars designated 'Rutgers Thunderstruck-DMR', 'Rutgers Passion-DMR', Rutgers Obsession-DMR&#x2019;, &#x2018;Rutgers Devotion-DMR&#x2019;, &#x2018;26_24_33&#x2019;, &#x2018;50_03_05&#x2019;, &#x2018;50_03_34&#x2019;, and &#x2018;42_21_02&#x2019; are provided, as are parts of the plants, extracts and biomasses from the variety, and uses thereof, for example as a food or in a food product. These plants have basil downy mildew resistance/tolerance.

Downy mildew resistant/tolerant sweet basil varieties

A clearing agent and mounting solution for microscopy is disclosed comprising (a) trichloroethanol, (b) optionally, trichloroacetic acid, (c) optionally, glycerol and (d) optionally, water, where the refractive index of the solution is greater than or equal to about 1.3810. The solution can further comprise a C1-C6 alcohol, other acids, and/or a stain. The solution can also comprise derivatives and/or analogs of 2,2,2-trichloroethanol and/or trichloroacetic acid. Also disclosed is a method of preparing specimens for microscopy comprising (a) applying a specimen to a microscope slide or a cuvette, (b) applying a quantity of the above solution sufficient to mount the specimen, and (c) optionally applying a cover slip. The solution can be used effectively with stains or dyes, and with fresh, partially dry or dried materials, and for temporary or semi-permanent to permanent mounting. The solution can be used with specimens or tissues/cells/parts originating from animals, poultry, livestock, humans, higher plants, yeasts, molds, microorganisms, insects, mites, or reptiles.

Clearing agent and mounting medium for microscopy

This disclosure concerns novel methods for preventing or treating neurological or neurodegenerative diseases or disorders by usingbutter acid enriched extracts derived from the seeds of African nutmeg, the main active compounds isolated from the extracts, namely sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, or synthetic analogs or derivatives thereof, as neuroprotective agents. The methods for preparing thebutter orbutter acid extracts and the methods for isolating and purifying the active compounds and for preparing their acetylated derivatives are also described.

Neuroprotective compositions and methods

This invention provides the methods of separation and identification of a novel type of piperidine flavan alkaloids from an African herbal tea, the leaves ofcommonly known as kinkeliba, and the procedures for preparing the total piperidine flavan alkaloids (TPFA). In particular, this invention relates to the use of the plant extract that may contain TPFA as anti-diabetic agents in treatment of metabolic disorders and other applications related to this new chemical structure and derivatives thereof.

Peperidine-flavan alkaloid compounds derived from African herb tea kinkeliba as anti-diabetic agents

The present invention relates to novel type of monoterpene synthase, a key enzyme in the production of the monoterpene aroma compound geraniol. More specifically, the present invention relates to nucleic acid sequences coding for GES from flowers and herbs species, in particular sweet basil, as well as to vectors containing the sequences, to host cells containing the sequences and to methods of producing recombinant GES, its products, and uses thereof.

Growing community of inventors

Princeton, NJ, United States of America

James E Simon