James Bertram

Title: Innovations of James Bertram in Intraocular Drug Delivery

Introduction

James Bertram is an accomplished inventor based in New Haven, CT (US). He has made significant contributions to the field of drug delivery systems, particularly in the management of intraocular pressure. His innovative work has led to the development of a patented technology that utilizes biodegradable polymeric microparticles for sustained drug delivery.

Latest Patents

James Bertram holds a patent for "Sustained intraocular delivery of drugs from biodegradable polymeric microparticles." This patent describes biodegradable polymeric microparticle compositions that contain one or more active agents useful for treating or preventing diseases or disorders of the eye. A preferred embodiment of this invention includes microparticle compositions that manage elevated intraocular pressure (IOP) in the eye. The invention employs relatively hydrophilic, carboxylated polymeric materials such as PLGA to enhance drug loading for water-soluble drugs like timolol maleate. The use of higher molecular weight polymers and a specific ratio of lactic acid (LA) to glycolic acid (GA) allows for a prolonged release of the drug over an extended period.

Career Highlights

Throughout his career, James Bertram has worked with prestigious institutions, including Yale University and the University of Iowa Research Foundation. His research has focused on innovative solutions to complex medical challenges, particularly in ophthalmology.

Collaborations

James has collaborated with notable professionals in his field, including Erin Lavik and Young H Kwon. Their combined expertise has contributed to advancements in drug delivery technologies.

Conclusion

James Bertram's innovative work in biodegradable polymeric microparticles represents a significant advancement in intraocular drug delivery systems. His contributions continue to impact the field of ophthalmology and improve patient outcomes.