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Years Active: 2022
Title: James B Hemphill: Innovator in Genome Editing Technology
Introduction
James B Hemphill is a prominent inventor based in Cambridge, MA (US). He is known for his groundbreaking work in the field of genome editing, particularly through the development of innovative CRISPR/Cas9 technologies. His contributions have significantly advanced the capabilities of genetic manipulation.
Latest Patents
Hemphill holds a patent for an "Activatable CRISPR/CAS9 for spatial and temporal control of genome editing." This invention discloses a genetically encoded light- or chemically-activated Cas9, engineered through the site-specific installation of an activatable lysine amino acid. The activatable Cas9 proteins can be utilized in CRISPR/Cas9 systems to control gene expression both temporally and spatially. The patent also provides systems, methods, kits, and compositions for manipulating sequences and/or activities of target sequences. Additionally, it includes methods for directing CRISPR complex formation in cells and selecting specific cells by introducing precise mutations using the CRISPR/Cas9 system. Hemphill's innovative approach has the potential to revolutionize genetic research and applications.
Career Highlights
Throughout his career, Hemphill has worked with esteemed institutions such as the University of Pittsburgh and the University of North Carolina at Chapel Hill. His experience in these research environments has allowed him to collaborate with leading scientists and contribute to significant advancements in genetic engineering.
Collaborations
Some of Hemphill's notable coworkers include Alexander Deiters and Aravind Asokan. Their collaborative efforts have further enhanced the research and development of CRISPR technologies.
Conclusion
James B Hemphill's contributions to the field of genome editing through his innovative patent and collaborative work have established him as a key figure in genetic research. His advancements in CRISPR technology continue to pave the way for future innovations in the field.