James A Thompson

Title: Innovations by James A Thompson

Introduction

James A Thompson is a notable inventor based in Aliso Viejo, CA (US). He has made significant contributions to the field of cancer immunotherapy, holding a total of 3 patents. His work focuses on enhancing immune responses to tumors, which has the potential to improve treatment outcomes for patients.

Latest Patents

Thompson's latest patents include innovative methods for cancer treatment. One of his inventions, titled "Enhanced immunogenic cell populations prepared using H2 receptor antagonists," provides a method to enhance alloactivation in a mixed lymphocyte culture. This invention aims to improve the effectiveness of alloactivated cells in treating tumors when implanted or coinjected with tumor cells as a vaccine. By enhancing alloactivation, more cell combinations can achieve a threshold of activation suitable for therapeutic use, leading to increased cytokine secretion during the proliferative phase.

Another significant patent is "Cancer immunotherapy using tumor cells combined with mixed lymphocytes." This invention comprises cellular vaccines and methods for their use in cancer immunotherapy, particularly in humans. The vaccines consist of stimulated lymphocytes that are allogeneic to the subject being treated, along with a source of tumor-associated antigen. The allogeneic lymphocytes can be stimulated by coculturing them with leukocytes from the subject or a third-party donor. This approach aims to prime or boost a systemic cellular anti-tumor immune response, potentially improving clinical outcomes.

Career Highlights

James A Thompson is affiliated with the University of California, where he continues to advance his research in immunotherapy. His work has garnered attention for its innovative approach to cancer treatment, focusing on harnessing the body's immune system to combat tumors effectively.

Collaborations

Thompson has collaborated with notable colleagues, including Gale Arthur Granger and John C Hiserodt. Their combined expertise contributes to the development of groundbreaking therapies in the field of cancer immunotherapy.

Conclusion

James A Thompson's contributions to cancer immunotherapy through his patents and research at the University of California highlight his commitment to improving patient outcomes. His innovative approaches have the potential to change the landscape of cancer treatment significantly.