Carmel, IN, United States of America

Jai P Singh


Average Co-Inventor Count = 2.3

ph-index = 9

Forward Citations = 311(Granted Patents)


Company Filing History:


Years Active: 1993-1999

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15 patents (USPTO):Explore Patents

Title: The Innovative Journey of Jai P Singh

Introduction

Jai P Singh, an accomplished inventor based in Carmel, Indiana, has made significant contributions to the field of biomedical research. With a total of 15 patents to his name, his work primarily focuses on innovations that have the potential to revolutionize therapeutic approaches for various angiogenic diseases.

Latest Patents

Among his notable inventions, Jai's latest patents include the development of modified platelet factor-4. This invention is based on discovering two modified forms of human platelet factor-4, known as MPF-4 and CPF-4, isolated from serum-free culture medium of lipopolysaccharide-stimulated peripheral blood leukocytes. Detailed amino acid sequence analysis indicates that MPF-4 shares homology with native platelet factor-4, enhancing its potential applications as a potent inhibitor of endothelial cell proliferation—approximately 10-100 fold more potent than native or recombinant platelet factor-4. This breakthrough makes MPF-4 and CPF-4 valuable tools for treating angiogenic diseases.

Additionally, Jai has developed methods to increase nitric oxide synthesis in vascular endothelial cells. This invention involves administering specific compounds to enhance nitric oxide concentration, thereby improving vascular health.

Career Highlights

His career encompasses significant experience in leading pharmaceutical companies, including Eli Lilly and Company and Lilly Industries, Inc. These positions have allowed him to foster innovation and contribute to impactful research projects in the biomedical field.

Collaborations

Throughout his career, Jai has collaborated with several talented professionals, including colleagues like Colin W Smith and George J Cullinan. These partnerships have played a vital role in advancing his research and patent applications, leading to a more profound impact on medical science.

Conclusion

In summary, Jai P Singh represents a pioneering spirit in the world of innovation and research. His extensive patent portfolio not only showcases his inventive capabilities but also highlights the potential of his work to transform treatments for angiogenic diseases. As he continues to advance the frontiers of biomedical science, the impact of his innovations will undoubtedly resonate in the healthcare industry for years to come.

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