Company Filing History:
Years Active: 1998-1999
Title: The Innovations of Jae Woon Lee: Pioneering Research in Nuclear Hormone Receptors
Introduction: Jae Woon Lee, an accomplished inventor based in Somerville, MA, has made significant contributions to the field of molecular biology. With three patents to his name, he is known for his innovative methods that enhance our understanding of nuclear hormone receptors and their interactions with various proteins.
Latest Patents: Among his latest contributions is a groundbreaking patent focused on nuclear thyroid hormone receptor-interacting polynucleotides. This patent discloses a method for determining whether a test protein can interact with a nuclear hormone receptor protein. The methodology involves the use of host cells containing a reporter gene linked to a protein binding site. Jae Woon Lee's invention outlines detailed processes involving first and second fusion genes that express specific fusion proteins, allowing for the determination of a test protein’s ability to influence reporter gene expression, thereby indicating its interaction with the nuclear hormone receptor. Such interactions can be hormone-dependent, hormone-independent, or hormone-sensitive. This work is crucial as it offers insights into thyroid hormone receptor-interacting proteins and the associated polypeptides.
Career Highlights: Jae Woon Lee currently works with The General Hospital Corporation, where he leverages his research background to advance biotechnological innovations. His dedicated work has positioned him at the forefront of scientific advancements related to hormone receptors, making a lasting impact in the medical and research communities.
Collaborations: Throughout his career, Jae Woon Lee has collaborated with talented professionals, including David D. Moore. Their combined expertise contributes significantly to the innovative projects undertaken at their institution, fostering a collaborative research environment that enhances scientific discovery.
Conclusion: Jae Woon Lee's contributions to the field of nuclear hormone receptor research underscore the importance of innovation in science. His patents not only demonstrate his expertise as an inventor but also pave the way for future research in understanding hormone interactions. As he continues his work at The General Hospital Corporation, the scientific community eagerly anticipates the future implications of his discoveries.