Westborough, MA, United States of America

Jae-Hyuck Shim

USPTO Granted Patents = 1 

Average Co-Inventor Count = 6.0

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2023

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1 patent (USPTO):

Title: The Innovative Contributions of Jae-Hyuck Shim in Gene Therapeutics

Introduction

Jae-Hyuck Shim, based in Westborough, Massachusetts, has made significant strides in the field of gene therapeutics with a focus on treating fibrodysplasia ossificans progressiva (FOP). FOP is a rare connective tissue disease characterized by the abnormal growth of bone in areas where bone should not form, leading to considerable physical impairment.

Latest Patents

Jae-Hyuck Shim holds a patent for "Gene Therapeutics for Fibrodysplasia Ossificans Progressiva." This patent encompasses innovative compositions and methodologies aimed at treating FOP by utilizing isolated nucleic acids and rAAV vectors. These vectors are designed to express transgenes that inhibit the mutated ACVR1 gene, thus decreasing its expression in muscle cells and connective tissues. This groundbreaking approach could potentially alter the course of treatment for those affected by this debilitating condition.

Career Highlights

Shim's career is marked by a dedicated pursuit of advancements in gene therapy, particularly in understanding and addressing genetic disorders. His work at the University of Massachusetts has positioned him as a prominent figure in his field, contributing to both academic knowledge and practical applications in medical interventions.

Collaborations

Throughout his career, Jae-Hyuck Shim has collaborated with esteemed colleagues, including Guangping Gao and Jun Xie. This collaborative environment fosters innovation and the sharing of ideas, crucial for the development of effective therapeutic solutions for complex medical challenges like FOP.

Conclusion

Jae-Hyuck Shim's contributions to gene therapeutics exemplify the vital intersection of research and practical application in medicine. His patent emphasizes the potential for innovative treatments that could improve the lives of individuals with fibrodysplasia ossificans progressiva, marking a significant advancement in genetic medicine. As he continues his work at the University of Massachusetts, the scientific community eagerly anticipates further breakthroughs from this dedicated inventor.

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