Jae Hwan Nam

Title: Innovations in Nucleic Acid Delivery by Jae Hwan Nam

Introduction

Jae Hwan Nam is a prominent inventor based in Bucheon-si, South Korea. He has made significant contributions to the field of pharmaceutical compositions, particularly in the delivery of nucleic acid drugs. His innovative work focuses on enhancing the stability and efficacy of these drugs through advanced lipid nanoparticle technology.

Latest Patents

Jae Hwan Nam holds a patent for a pharmaceutical composition of lipid nanoparticles designed for delivering nucleic acid drugs containing trehalose derivatives and novel structure-maintaining lipid compounds. This patent discloses a unique composition of lipid nanoparticles that stabilizes nucleic acid drugs and enhances their delivery in vivo. The lipid nanoparticles include a nucleic acid drug and various lipids, which encompass mRNA-based vaccines, RNA for immune boosters, miRNA, siRNA, pDNA, and antisense ODN. The lipid component consists of a trehalose-based lipid, an ionizable lipid, a phospholipid, a PEG-lipid, and a structure-maintaining lipid. This innovative structure-maintaining lipid can replace commonly used cholesterol with derivatives of lithocholic acid, glycyrrhetinic acid, or diosgenin. The versatility of these lipid nanoparticles allows them to be utilized as either vaccines or therapeutic agents, depending on the type of nucleic acid drug employed.

Career Highlights

Jae Hwan Nam is currently associated with SML Biopharm Co., Ltd., where he continues to advance his research in biopharmaceuticals. His work has garnered attention for its potential applications in vaccine development and therapeutic interventions.

Collaborations

He collaborates with notable colleagues, including Eun Kyoung Bang and Gyo Chang Keum, who contribute to the innovative research environment at SML Biopharm Co., Ltd.

Conclusion

Jae Hwan Nam's contributions to the field of nucleic acid drug delivery through lipid nanoparticles represent a significant advancement in pharmaceutical technology. His innovative approaches have the potential to enhance the efficacy of vaccines and therapeutic agents, paving the way for future developments in biopharmaceuticals.