IDiyas

For the Inventor, By the Inventor

Bures-sur-Yvette, France

Jacques Bartholeyns

USPTO Granted Patents = 12

Average Co-Inventor Count = 2.1

ph-index = 3

Forward Citations = 33(Granted Patents)


Location History:

  • Bures-sur-Yvette, FR (1997 - 2004)
  • Turquant, FR (2004 - 2005)

Company Filing History:

goldMedal9 out of 17 
 
I.d.m. Immuno-designed Molecules
 patents
silverMedal1 out of 1 
 
I.d.m. Immuno-designed
 patent
bronzeMedal2 out of 832,718 
Other
 patents

Years Active: 1997-2005

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12 patents (USPTO):Explore Patents
1. 6881413 - Humanized biomaterials, a process for their preparation and their applications (2005-04-19),
2. 6821516 - Macrophages, process for preparing the same and their use as active substances of pharmaceutical compositions (2004-11-23),
3. 6737051 - Cell compositions containing macrophages, presenting anti-infectious and hematopoietic properties (2004-05-18),
4. 6713056 - Combined preparation for the treatment of neoplasic diseases or of infectious diseases (2004-03-30),
5. 6703016 - Apoptotic bodies, monocyte derived cells containing the same, a process for their preparation and their uses as vaccines (2004-03-09),
6. 6616925 - Combined preparation for the treatment of neoplasic diseases or of infectious diseases (2003-09-09),
7. 6596275 - Monocyte derived cells with immunosuppressive properties, process for their preparation and their uses in pharmaceutical compositions (2003-07-22),
8. 6540994 - Macrophages, process for preparing the same and their use as active substances of pharmaceutical compositions (2003-04-01),
9. 6399372 - Monocyte derived cells with immunostimulating properties, their preparation and uses (2002-06-04),
10. 6051432 - Macrophages, process for preparing the same and their use as active (2000-04-18),
11. 6001351 - Macrophages, process for preparing the same and their use as active (1999-12-14),
12. 5662899 - Macrophages, process for preparing the same and their use as active (1997-09-02),

Title: The Innovative Mind of Jacques Bartholeyns

Introduction

Jacques Bartholeyns, a prolific inventor based in Bures-sur-Yvette, France, has made significant contributions to the field of biomedical engineering. With a remarkable portfolio containing 12 patents, Bartholeyns focuses on advancing humanized biomaterials and their applications in medicine. His innovative spirit and dedication position him as a notable figure in the realm of scientific discovery.

Latest Patents

Among his latest patents, Bartholeyns has developed cutting-edge technologies related to humanized biomaterials. One notable invention involves a porous biocompatible composite material implanted with monocyte-derived cells, preferably macrophages. This innovation emphasizes the customization and preparation processes that enhance the biocompatibility of materials used in medical applications.

Additionally, he has made strides in improving the properties of macrophages. His invention describes macrophages that possess enhanced cytotoxic activity—showing an increase of approximately 20% to 30% without the presence of IFN-γ compared to standard macrophages. Furthermore, his research highlights a significant increase in cytotoxic activity with IFN-γ, achieving up to about 93%. Bartholeyns’ work on extending the deactivation of cytotoxic activity post-IFN-γ activation reveals critical insights for therapeutic development targeting tumoral cells, particularly U 937 cells.

Career Highlights

Throughout his career, Jacques Bartholeyns has established himself within notable companies specializing in innovative biomedical solutions. Among these, he has worked at Immuno-Designed Molecules, where he contributed significantly to advancing research and application of immunological therapies. His dedication to translating scientific research into practical applications has been a hallmark of his professional journey.

Collaborations

Collaboration is a vital part of any inventor's journey, and Bartholeyns has teamed up with esteemed colleagues, including Mohamed Chokri and Jean-Loup Romet-Lemonne. Their collective expertise has enriched Bartholeyns' projects and facilitated breakthroughs in the realm of humanized biomaterials and cellular therapies.

Conclusion

Jacques Bartholeyns exemplifies the spirit of innovation within the scientific community. His substantial contributions to the development of humanized biomaterials and enhanced macrophage functionality continue to pave the way for advancements in medical applications. As he moves forward, his work will undoubtedly inspire future generations of inventors and researchers.

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