Company Filing History:
Years Active: 2024
Title: Jacobus Cornelis Rasser: Innovator in Antibody Engineering
Introduction
Jacobus Cornelis Rasser is a notable inventor based in Ghent, Belgium. He has made significant contributions to the field of antibody engineering, particularly through his innovative methods for preparing pH-dependent antibodies. His work has implications for the development of more effective therapeutic antibodies.
Latest Patents
Rasser holds a patent for a "Method of preparing pH-dependent antibodies." This patent discloses methods for preparing engineered antibodies that exhibit improved pH-dependent antigen binding. The techniques involve the introduction of histidine residues at specific amino acid positions within the antibody CDRs. The selection of these positions is based on a heat-map analysis of histidine occurrence in functional antibodies from a natural repertoire. This approach simplifies and accelerates the identification of pH-dependent antibody variants.
Career Highlights
Jacobus Cornelis Rasser is associated with Argenx Bv, a company known for its focus on innovative antibody therapies. His work at Argenx has positioned him as a key player in the advancement of therapeutic antibody technologies. Rasser's contributions are vital in enhancing the efficacy of antibody-based treatments.
Collaborations
Rasser collaborates with esteemed colleagues such as Christophe Blanchetot and Erik Hofman. Their combined expertise fosters a productive environment for innovation in antibody research and development.
Conclusion
Jacobus Cornelis Rasser's work in the field of antibody engineering exemplifies the impact of innovative methods on therapeutic advancements. His patent for preparing pH-dependent antibodies represents a significant step forward in the development of effective treatments.