Company Filing History:
Years Active: 2015-2025
Title: Innovations by Jacob Pade Ramsoe Jacobsen
Introduction
Jacob Pade Ramsoe Jacobsen is an accomplished inventor based in Durham, NC (US). He has made significant contributions to the field of pharmaceuticals, particularly in enhancing the efficacy of treatments involving 5-hydroxytryptophan (5-HTP). With a total of 5 patents, Jacobsen's work focuses on innovative methods to improve therapeutic outcomes for patients with psychiatric and neurological disorders.
Latest Patents
Jacobsen's latest patents include a method of enhancing 5-hydroxytryptophan (5-HTP) exposure. This patent describes a gastroretentive, sustained-release dosage form that includes 5-HTP as an active ingredient along with low-dose carbidopa. The dosage form can be provided as a bilayer tablet comprising a swelling layer and a modified release layer. Both 5-HTP and carbidopa are included in the modified release layer, allowing for essentially parallel release of the two compounds. For instance, 80% of the 5-HTP and carbidopa can be released within about 5 to 12 hours. Additionally, Jacobsen has developed methods for optimizing 5-hydroxytryptamine function in the brain for therapeutic purposes. These methods involve elevating brain extracellular 5-hydroxytryptamine (5-HT) levels through continuous intravenous infusion of 5-HTP, providing rapid therapeutic effects with minimal adverse effects.
Career Highlights
Throughout his career, Jacobsen has worked with notable organizations such as Evecxia Therapeutics, Inc. and Duke University. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Jacobsen has collaborated with various professionals, including his coworker Brian Frøstrup. These partnerships have facilitated the development of innovative solutions in the realm of psychiatric and neurological treatments.
Conclusion
Jacob Pade Ramsoe Jacobsen is a prominent inventor whose work in enhancing 5-HTP therapies has the potential to significantly impact the treatment of psychiatric and neurological disorders. His innovative approaches and collaborations continue to pave the way for advancements in pharmaceutical science.