Jacob M Tome

Title: Jacob M Tome: Innovator in RNA Interaction Assays

Introduction

Jacob M Tome is a notable inventor based in Ithaca, NY (US). He has made significant contributions to the field of molecular biology, particularly in the development of methods for detecting RNA interactions. His innovative approach has the potential to advance research in various biological processes.

Latest Patents

Jacob M Tome holds a patent for a "High-throughput RNA interaction assay." This invention is directed to a method for detecting an interaction between a ribonucleic acid (RNA) molecule and a second molecule. The method involves providing a nucleic acid construct that contains a promoter sequence, a nucleotide sequence encoding the RNA molecule, and an RNA polymerase blocking site. The nucleotide sequence encoding the RNA molecule is transcribed in vitro to produce an RNA transcript corresponding to the RNA molecule. Transcription is halted by the RNA polymerase blocking site under conditions effective for the RNA transcript to remain tethered to the nucleic acid construct. The tethered RNA transcript is then contacted with the second molecule, and any interaction between the tethered RNA transcript and the second molecule is detected and identified based on the contacting.

Career Highlights

Jacob M Tome is affiliated with Cornell University, where he conducts his research and development work. His innovative contributions have garnered attention in the scientific community, particularly for their applications in understanding RNA interactions.

Collaborations

Some of his notable coworkers include John T Lis and Abdullah Ozer. Their collaborative efforts contribute to the advancement of research in molecular biology and related fields.

Conclusion

Jacob M Tome is a distinguished inventor whose work in RNA interaction assays exemplifies the intersection of innovation and scientific research. His contributions continue to influence the field and pave the way for future discoveries.