Jacob Giehm Mikkelsen

Title: Jacob Giehm Mikkelsen: Innovator in Genetic Modification

Introduction

Jacob Giehm Mikkelsen is a notable inventor based in Silkeborg, Denmark. He has made significant contributions to the field of genetic modification, particularly in the development of genetically modified pigs. His work has implications for both agricultural practices and medical research.

Latest Patents

Mikkelsen holds 2 patents that showcase his innovative approach to genetic engineering. His first patent involves a genetically modified pig whose genome comprises a heterologous site-specific recombination site and a transposon tag. This invention relates to a pig that includes at least one site for the integration of transgenes, as well as various developmental stages such as embryos and blastocysts derived from this genetically modified pig.

The second patent focuses on a genetically modified pig model for studying atherosclerosis. This modified pig displays phenotypes associated with the disease and includes mutations in key genes related to lipid metabolism. The invention also outlines methods for producing this modified pig and evaluating therapeutic treatments for atherosclerosis.

Career Highlights

Jacob Giehm Mikkelsen is affiliated with Aarhus Universitet, where he conducts his research and development work. His innovative contributions have positioned him as a key figure in the field of genetic modification.

Collaborations

Mikkelsen has collaborated with notable colleagues such as Peter Michael Kragh and Lars Bolund. These partnerships have further enhanced the impact of his research in genetic engineering.

Conclusion

Jacob Giehm Mikkelsen's work in genetic modification, particularly with pigs, represents a significant advancement in both agricultural and medical research. His patents reflect a commitment to innovation that could lead to breakthroughs in understanding and treating diseases like atherosclerosis.