This inventor holds 3 USPTO granted patents. Top assignees: Abbott Laboratories Corporation, University of Cincinnati, Other. Active years: 1982-2003.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
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1 out of 834,453 Years Active: 1982-2003
Title: Jacob Gabriel Michael: Innovator in Therapeutic Proteins
Introduction
Jacob Gabriel Michael is a notable inventor based in Cincinnati, OH (US). He has made significant contributions to the field of therapeutic proteins, holding a total of 3 patents. His innovative work focuses on enhancing the delivery and efficacy of therapeutic proteins through novel methods.
Latest Patents
One of Jacob's latest patents is titled "Oral administration of therapeutic proteins." This invention provides an orally administrable therapeutic protein by combining it with a stabilizing agent in an aqueous solution. The solution is coated onto nonpareils and microencapsulated with a water emulsifiable enteric coating composition. This microencapsulation protects the protein as it passes through the stomach. Upon reaching the small intestines, the basic pH of the intestinal juices dissolves the coating, allowing the protein to be released and induce an antigen-specific immune response that mirrors the specificity of the native molecule. The stabilizing agent plays a crucial role in protecting the therapeutic protein from denaturation during the encapsulation process.
Another significant patent is "Method of immunization with partially cationized substances." This invention involves a partially cationized protein-containing substance that exhibits enhanced immunogenicity compared to the native protein-containing substance. It is useful in mammalian immunization through oral or parenteral administration.
Career Highlights
Jacob has worked with the University of Cincinnati, where he has contributed to various research initiatives. His work has been instrumental in advancing the understanding and application of therapeutic proteins in medical treatments.
Collaborations
Throughout his career, Jacob has collaborated with notable individuals such as Allen Litwin and Amadeo J Pesce. These collaborations have further enriched his research and innovation in the field.
Conclusion
Jacob Gabriel Michael is a pioneering inventor whose work in therapeutic proteins has the potential to revolutionize medical treatments. His innovative patents and collaborations highlight his commitment to advancing healthcare solutions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile