Jacob Borrajo

Title: Jacob Borrajo: Innovator in CRISPR Technology

Introduction

Jacob Borrajo is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of genetic engineering, particularly through his work with CRISPR technology. With a total of 5 patents, Borrajo is recognized for his innovative approaches to gene editing and cellular monitoring.

Latest Patents

One of Jacob Borrajo's latest patents is titled "Targeted trans-splicing using CRISPR/Cas13." This disclosure provides compositions and methods for mediating a targeted trans-splicing event on a pre-mRNA in a cell. Another notable invention is "Constructs for continuous monitoring of live cells." This invention offers methods to obtain multiple information-rich samples at different time points from the same cell while minimally disrupting the cell. The subject matter is related to nucleic acid constructs that enable live cells to self-report cellular contents while maintaining cell viability. This innovation may be used to monitor gene expression in single cells effectively.

Career Highlights

Jacob Borrajo has worked with prestigious institutions such as the Massachusetts Institute of Technology and the Broad Institute, Inc. His work at these organizations has allowed him to push the boundaries of genetic research and contribute to advancements in biotechnology.

Collaborations

Throughout his career, Borrajo has collaborated with notable colleagues, including Paul Blainey and Mohamad Najia. These partnerships have fostered a collaborative environment that enhances innovation and research in the field.

Conclusion

Jacob Borrajo is a leading figure in the realm of genetic engineering, with a focus on CRISPR technology and cellular monitoring. His contributions through patents and collaborations continue to shape the future of biotechnology.