Jack Wuyang Jin

Title: Jack Wuyang Jin: Innovator in Protein Targeting Technologies

Introduction

Jack Wuyang Jin is a prominent inventor based in Vancouver, Canada. He has made significant contributions to the field of biotechnology, particularly in the development of innovative peptide-based technologies. With a total of three patents to his name, Jin is recognized for his groundbreaking work in protein knockdown methods.

Latest Patents

One of Jin's latest patents focuses on a peptide directed protein knockdown. This invention provides a peptide that includes a chaperone-mediated autophagy (CMA)-targeting signal domain, a protein-binding domain that selectively binds to a target cytosolic protein, and a cell membrane penetrating domain (CMPD). The invention outlines methods for reducing the intracellular expression level of an endogenous target protein both in vitro and in animal models. Additionally, it offers methods for treating pathological conditions in animals, particularly neurodegenerative diseases. In one embodiment, the target cytosolic protein is death associated protein kinase 1, and the CMPD is the protein transduction domain of the HIV-1 Tat protein.

Career Highlights

Jack Wuyang Jin is affiliated with the University of British Columbia, where he continues to advance his research in protein targeting technologies. His work has garnered attention for its potential applications in treating various diseases, particularly those related to neurodegeneration.

Collaborations

Jin collaborates with notable colleagues, including Yu Tian Wang and Xuelai Fan, who contribute to his research endeavors and help further the impact of his innovations.

Conclusion

Jack Wuyang Jin is a distinguished inventor whose work in peptide directed protein knockdown holds promise for advancing therapeutic strategies in biotechnology. His contributions continue to shape the landscape of protein targeting technologies.