Company Filing History:
Years Active: 1996
Title: Jack H Lichy: Innovator in Tumor Suppressor Gene Research
Introduction
Jack H Lichy is a prominent inventor based in Silver Spring, MD (US). He is known for his significant contributions to the field of genetics, particularly in the identification of tumor suppressor genes. His work has implications for cancer research and potential gene therapy applications.
Latest Patents
Jack H Lichy holds a patent for the HTS-1 gene, a human tumor suppressor gene. This gene is associated with tumor suppression and is localized on chromosome 11. The identification, localization, and sequence of this gene demonstrate differential expression that correlates with tumorigenicity. This suggests that the HTS-1 gene could potentially be utilized for gene therapy in cancers where its expression is deleted or altered. Furthermore, the gene's localization on chromosome 11p15, along with identified polymorphisms, allows for the analysis of tumor DNA for loss of heterozygosity at this chromosome region. The frequent loss of heterozygosity (LOH) in many human malignancies indicates that determining LOH at chromosome 11p15 may be useful in predicting tumor prognosis.
Career Highlights
Jack H Lichy is affiliated with the United States of America as represented by the Department of Health. His work in this capacity has allowed him to contribute to significant advancements in cancer research and gene therapy.
Collaborations
Jack has collaborated with notable professionals in his field, including Peter M Howley. Their joint efforts have furthered the understanding of tumor suppressor genes and their potential applications in medicine.
Conclusion
Jack H Lichy's work in identifying the HTS-1 gene marks a significant advancement in cancer research. His contributions have the potential to influence future gene therapy approaches for cancer treatment.