Company Filing History:
Years Active: 1985-1987
Title: Innovations of Jacinta Skelly in Hepatitis B Vaccine Development
Introduction
Jacinta Skelly is a prominent inventor based in Cardiff, GB. She has made significant contributions to the field of vaccine development, particularly in relation to hepatitis B. With a total of 2 patents, her work has garnered attention for its innovative approach to immunogenicity.
Latest Patents
Jacinta's latest patents focus on immunogenically active fragments of the hepatitis B surface antigen. These fragments include a glycoprotein of molecular weight about 28,000 (gp 28) and a protein of molecular weight about 23,000 (p 23). They are prepared in micelle form that is substantially free from detergent. The micelles are at least as immunogenic as the unfragmented antigen from which they are derived, making them useful in the preparation of hepatitis B vaccines. The process involves layering the detergent-containing fragmentation product on an aqueous buffer with a sucrose gradient and centrifuging it. This method allows for the recovery of micelles containing both gp 28 and p 23 in a substantially detergent-free form.
Career Highlights
Jacinta Skelly is associated with the National Research Development Corporation, where she has been instrumental in advancing research in vaccine technology. Her innovative work has positioned her as a key figure in the field of immunology.
Collaborations
Jacinta has collaborated with notable coworkers, including Colin R Howard and Arie J Zuckerman. These partnerships have further enhanced her research and development efforts in the field.
Conclusion
Jacinta Skelly's contributions to hepatitis B vaccine development highlight her innovative spirit and dedication to improving public health. Her patents reflect a significant advancement in vaccine technology, showcasing her role as a leading inventor in this critical area.