Company Filing History:
Years Active: 2019
Title: Jacinta L Chuang: Innovator in Mitochondrial Research
Introduction
Jacinta L Chuang is a prominent inventor based in Dallas, TX (US). She has made significant contributions to the field of mitochondrial research, particularly in the development of inhibitors for mitochondrial pyruvate dehydrogenase kinase (PDK) isoforms. Her work has implications for treating various diseases, including diabetes, cardiovascular disease, and cancer.
Latest Patents
Jacinta holds a patent titled "Inhibitors of mitochondrial pyruvate dehydrogenase kinase isoforms 1-4 and uses thereof." This patent focuses on the identification of PDK inhibitors and their therapeutic applications. The invention aims to improve glucose metabolism and correct metabolic dysfunction in vivo. By making a single functional-group change in a known Hsp90 inhibitor, Jacinta developed a highly specific inhibitor for all PDK isoforms. This innovative approach enhances PDC activity while reducing phosphorylation in tissues.
Career Highlights
Jacinta is affiliated with the University of Texas System, where she continues her research and development efforts. Her work has garnered attention for its potential to address critical health issues through innovative solutions.
Collaborations
Jacinta collaborates with notable colleagues, including David T Chuang and Shih-Chia Tso. Their combined expertise contributes to advancing research in mitochondrial function and metabolic diseases.
Conclusion
Jacinta L Chuang is a trailblazer in mitochondrial research, with her patent offering promising avenues for treating metabolic disorders. Her contributions to science and medicine highlight the importance of innovation in addressing complex health challenges.