J William Efcavitch

Title: J William Efcavitch: Innovator in Oligonucleotide Synthesis

Introduction

J William Efcavitch is a notable inventor based in Belmont, CA (US). He has made significant contributions to the field of oligonucleotide synthesis, particularly through his innovative methods that enhance the efficiency and effectiveness of this complex process.

Latest Patents

Efcavitch holds a patent for a method titled "Chemical capping by phosphitylation during oligonucleotide synthesis." This patent describes a technique for capping failure sequences in oligonucleotide synthesis by phosphitylation. Specifically, a phosphite monoester is reacted with the 5' or 3' hydroxyl of the failure sequence between successive condensation steps. This reaction forms a 5' or 3' phosphite diester with the failure sequence, which remains inert during subsequent reaction steps in the synthesis of the desired oligonucleotide product. He has 1 patent to his name.

Career Highlights

Efcavitch has worked with Applied Biosystems, LLC, a company known for its advancements in biotechnology and genetic analysis. His work has contributed to the development of more efficient methods in the synthesis of oligonucleotides, which are essential for various applications in genetic research and therapeutics.

Collaborations

Throughout his career, Efcavitch has collaborated with notable colleagues, including William A Andrus and Lincoln J McBride. These collaborations have furthered the research and development of innovative solutions in the field of biotechnology.

Conclusion

J William Efcavitch's contributions to oligonucleotide synthesis through his patented methods demonstrate his commitment to advancing biotechnology. His work continues to influence the field and pave the way for future innovations.