Company Filing History:
Years Active: 2000-2004
Title: J Steven Alexander: Innovator in Cancer Therapy and Gene Regulation
Introduction
J Steven Alexander is a notable inventor based in Shreveport, Louisiana. He has made significant contributions to the fields of cancer therapy and gene regulation, holding a total of 4 patents. His innovative work focuses on developing methods and compounds that enhance medical treatments and improve patient outcomes.
Latest Patents
One of his latest patents involves compounds and methods for cancer therapy. This invention provides methods for using modulating agents to enhance or inhibit occludin-mediated cell adhesion in various in vivo and in vitro contexts. The modulating agents can be utilized for cancer therapy or to increase immune cell infiltration into tumors. These agents comprise at least one occludin cell adhesion recognition sequence or an antibody that specifically binds to this sequence. Additionally, the modulating agents may include other cell adhesion recognition sequences recognized by different adhesion molecules.
Another significant patent by Alexander focuses on the selective regulation of DNA and RNA transcription and translation through photoactivation. This invention features an isolated nucleic acid that is covalently linked to a photolabile caging group, which reversibly prevents the expression of the nucleic acid. The method allows for the selective expression of nucleic acids in cells by introducing the nucleic acid and exposing the cell to light, which unlinks the nucleic acid from the caging group, enabling its expression.
Career Highlights
Throughout his career, J Steven Alexander has worked with prestigious organizations, including Vanderbilt University and Adherex Technologies, Inc. His experience in these institutions has contributed to his expertise in developing innovative solutions in the medical field.
Collaborations
Alexander has collaborated with notable professionals in his field, including Frederick R Haselton and Orest W Blaschuk. These collaborations have further enhanced his research and development efforts.
Conclusion
J Steven Alexander's contributions to cancer therapy and gene regulation demonstrate his commitment to advancing medical science. His innovative patents reflect a deep understanding of complex biological processes and a dedication to improving patient care.