Izuru Tokumaru

Title: Izuru Tokumaru: Innovator in Fumaric Acid Production

Introduction

Izuru Tokumaru is a notable inventor based in Inashiki-gun, Japan. He has made significant contributions to the field of biochemistry, particularly in the production of fumaric acid and L-aspartic acid. With a total of 2 patents to his name, Tokumaru's work showcases the intersection of microbiology and chemical engineering.

Latest Patents

Tokumaru's latest patents include innovative methods for producing fumaric acid. One method involves reacting a culture of a microorganism that produces maleate isomerase, which exhibits maximum activity at temperatures of 50 degrees Celsius or higher, with maleic acid in an aqueous solution. This process is designed to isomerize maleic acid to produce fumaric acid. Another patent details a method for producing fumaric acid by reacting maleic acid in an aqueous solution with a microorganism that has maleate isomerase activity. This enzymatic isomerization is carried out under conditions that maintain the dissolved oxygen concentration at 4 ppm or less, utilizing gases such as nitrogen, argon, or helium to seal the reaction solution.

Career Highlights

Izuru Tokumaru is currently employed at Mitsubishi Chemical Corporation, where he continues to advance his research and development efforts. His work has not only contributed to the scientific community but also has practical applications in various industries.

Collaborations

Throughout his career, Tokumaru has collaborated with esteemed colleagues, including Makoto Goto and Masato Terasawa. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.

Conclusion

Izuru Tokumaru's contributions to the production of fumaric acid and L-aspartic acid highlight his role as a significant inventor in the field of biochemistry. His innovative methods and collaborations continue to influence the industry and pave the way for future advancements.