Iwao Ohtsu

Title: Iwao Ohtsu: Innovator in L-Cysteine Production

Introduction

Iwao Ohtsu is a notable inventor based in Ikoma, Japan. He has made significant contributions to the field of biotechnology, particularly in the production of L-cysteine. With a total of 3 patents, his work has paved the way for more efficient methods of producing this important amino acid.

Latest Patents

Ohtsu's latest patents focus on the modification of Enterobacteriaceae bacteria to enhance their ability to produce L-cysteine. One of his inventions describes a bacterium modified to reduce the activity of O-acetylserine sulfhydrylase B, which allows for inexpensive and efficient L-cysteine production. This bacterium has a deleted C terminal region of its thiosulfate-binding protein and shows increased L-cysteine production in the presence of sulfate. Another patent presents a method for producing L-cysteine using a modified Enterobacteriaceae bacterium that increases the activity of the protein encoded by the dsbA gene. This bacterium can be cultured in a medium to collect L-cysteine, L-cystine, or their derivatives.

Career Highlights

Throughout his career, Ohtsu has worked with prominent organizations such as Ajinomoto Co., Ltd. and the Nara Institute of Science and Technology. His work in these institutions has contributed to advancements in biotechnology and the efficient production of essential compounds.

Collaborations

Ohtsu has collaborated with notable colleagues, including Hiroshi Takagi and Gen Nonaka. Their combined expertise has furthered research and development in the field of biotechnology.

Conclusion

Iwao Ohtsu's innovative work in the modification of bacteria for L-cysteine production highlights his significant contributions to biotechnology. His patents and collaborations reflect a commitment to advancing scientific knowledge and practical applications in the industry.