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Years Active: 2024
Title: Itay Tirosh: Innovator in Cancer Research
Introduction
Itay Tirosh is a prominent inventor based in Cambridge, MA, known for his significant contributions to cancer research. He holds 3 patents that focus on innovative methods and compositions for treating various forms of cancer, particularly gliomas.
Latest Patents
One of his latest patents is titled "Methods and compositions for targeting developmental and oncogenic programs in H3K27M gliomas." This patent discloses compositions and methods aimed at treating diffuse gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-gliomas). The invention includes gene signatures specific for tumor cell types and treatment compositions targeting PRC1 in H3K27M-gliomas.
Another notable patent is "Methods and compositions for treating cancer by targeting the CLEC2D-KLRB1 pathway." This patent provides methods and compositions for treating cancer by blocking the interaction of KLRB1 with its ligand, which is crucial for inhibiting the cytotoxic function of NK cells. The agent may include an antibody or fragment that binds to KLRB1 or CLEC2D, showcasing Tirosh's innovative approach to cancer treatment.
Career Highlights
Itay Tirosh has worked with esteemed organizations such as Dana-Farber Cancer Institute and the Broad Institute. His work in these institutions has significantly advanced the understanding and treatment of cancer.
Collaborations
Throughout his career, Tirosh has collaborated with notable figures in the field, including Aviv Regev and Mario Suva. These collaborations have further enriched his research and contributions to cancer treatment.
Conclusion
Itay Tirosh is a leading inventor whose work in cancer research has led to innovative patents that aim to improve treatment outcomes for patients. His dedication to advancing medical science is evident in his impactful contributions.