This inventor holds 3 USPTO granted patents and 2 published patent applications. Top assignee: Yeda Research and Develpment & Co. Ltd. Active years: 2010-2015.
Company Filing History:
Years Active: 2010-2015
Title: Israel Silman: Innovator in Enzymatic Research
Introduction
Israel Silman is a prominent inventor based in Rehovot, Israel. He has made significant contributions to the field of enzymatic research, holding a total of 3 patents. His work focuses on polypeptides and polynucleotides, which have important implications in biotechnology and medicine.
Latest Patents
Silman's latest patents include innovative methods and compositions related to PON polypeptides and glucocerebrosidase. One of his notable patents involves isolated polynucleotides and polypeptides encoded from mutated PON enzymes. These enzymes exhibit increased or modified substrate specificity compared to their wild-type counterparts. Additionally, he has developed methods for identifying compounds that can correct impaired enzymatic activity in mutant glucocerebrosidase molecules. This involves computational techniques to generate 3D structures of these molecules, facilitating the discovery of corrective compounds.
Career Highlights
Israel Silman is associated with Yeda Research and Development Co. Ltd., where he continues to advance his research. His work has garnered attention for its potential applications in treating genetic disorders related to enzyme deficiencies. His innovative approaches have positioned him as a key figure in enzymatic research.
Collaborations
Some of his notable coworkers include Joel L. Sussman and Dan S. Tawfik. Their collaborative efforts have contributed to the advancement of research in enzymatic functions and applications.
Conclusion
Israel Silman's contributions to enzymatic research through his patents and collaborations highlight his role as an influential inventor in the field. His work continues to pave the way for advancements in biotechnology and medicine.