Company Filing History:
Years Active: 1997-2003
Title: The Innovative Contributions of Irving Shapiro
Introduction
Irving Shapiro, based in Philadelphia, PA, is a notable inventor with a remarkable portfolio of seven patents. His contributions to the field of biomedical engineering have significantly advanced our understanding of intervertebral disc health and recovery.
Latest Patents
One of Shapiro's latest patents focuses on the "Preparation of polymer foam having gelled sol coating for intervertebral disc reformation." This innovative approach provides methods and materials aimed at reforming degenerated intervertebral discs in vertebrates, particularly humans. The process begins with the evacuation of tissue from the nucleus pulposus portion of a degenerated intervertebral disc. A biodegradable substrate, which contains isolated intervertebral disc cells, is then implanted into the evacuated space to facilitate the reformation of intervertebral disc tissue.
The patent outlines a method for obtaining intervertebral disc cells through the digestion of intervertebral disc tissue with collagenase as well as incubation in a medium supplemented with hyaluronidase. Additionally, the patent discusses the use of bioactive substrates, including bioactive glass granules and polymer foams coated with a bioactive gel material produced by a sol-gel process. The polymer foam employed may be poly(D,L-lactide-co-glycolide), and the bioactive gel typically consists of 70% SiO, 25% CaO, and 5% P2O5.
Career Highlights
Shapiro has had a distinguished career, with significant experiences at the University of Pennsylvania and the Trustees of the University of Pennsylvania. His work has focused on various aspects of biomedical applications, particularly in the area of spinal health.
Collaborations
Throughout his career, Irving Shapiro has collaborated with esteemed colleagues such as Paul Ducheyne and Ahmed El-Ghannam. Together, they have pushed the boundaries of innovation in the realm of tissue engineering and regenerative medicine.
Conclusion
Irving Shapiro's innovative spirit and commitment to improving human health through advanced biomedical solutions have led to valuable contributions within his field. His patents reflect a dedication to finding effective treatments for degenerative conditions, bringing hope and recovery to many individuals suffering from intervertebral disc issues.