Location History:
- Fair Lawn, NJ (US) (1998 - 2006)
- Woodbridge, CT (US) (2011 - 2016)
Company Filing History:
3 out of 1,627 
2 out of 1,327 
1 out of 157 
Years Active: 1998-2016
Title: The Impactful Innovations of Irit Lax in Receptor Tyrosine Kinase Research
Introduction
Irit Lax, an accomplished inventor based in Woodbridge, CT, has made significant contributions to the field of receptor tyrosine kinase research. With a remarkable portfolio of five patents, her work focuses on therapeutic applications that address critical health issues related to skeletal disorders and receptor signaling pathways.
Latest Patents
Irit's latest patents include groundbreaking inventions aimed at inhibiting receptor tyrosine kinases. One pivotal invention provides moieties that bind to Ig-like domains of human receptor tyrosine kinases, such as the Kit RTK or PDGFR RTK. This innovation effectively locks the ectodomain of the receptor tyrosine kinase in an inactive state, antagonizing its activity.
Another significant patent outlines a method for treating skeletal disorders resulting from fibroblast growth factor receptor (FGFR) malfunction. This invention encompasses materials and methods for identifying agents that target diseases arising from excessive FGF receptor signaling. These agents are invaluable in treating various craniofacial disorders linked to FGFR malfunction, including syndromes such as Crouzon, Apert, and Jackson-Weiss.
Career Highlights
Irit has had a distinguished career, with key positions at prestigious institutions such as New York University and Yale University. Her research endeavors have been pivotal in advancing our understanding of receptor tyrosine kinases and their implications in various diseases.
Collaborations
Throughout her career, Irit has collaborated with notable figures in the field, including Joseph Schlessinger and Haruhiko Kouhara. These partnerships have fostered a collaborative environment conducive to groundbreaking discoveries and innovations in receptor tyrosine kinase research.
Conclusion
Irit Lax stands out as a transformative inventor whose patents have the potential to revolutionize treatments for skeletal disorders and improve our understanding of receptor signaling pathways. Her contributions not only enhance scientific knowledge but also pave the way for future therapeutic advancements that could benefit countless individuals.