This inventor holds 1 USPTO granted patent. Top assignee: Reanal Finomvegyszergyar. Active years: 1985.
Company Filing History:
Years Active: 1985
Title: Iren Huber: Innovator in Aminoacylase Isolation
Introduction
Iren Huber is a notable inventor based in Budapest, Hungary. He has made significant contributions to the field of biochemistry, particularly in the isolation of aminoacylase. His innovative methods have the potential to streamline processes in biochemical applications.
Latest Patents
Iren Huber holds a patent for a method of isolating aminoacylase from mammal kidneys. The process involves comminuting and homogenizing mammal kidney in water, followed by centrifugation to form an aqueous extract. The extract is then heated at temperatures between 60 to 80 degrees Celsius for 5 to 15 minutes, after which it undergoes further centrifugation. A salt, such as ammonium sulfate, is added to the supernatant, and additional centrifugation separates the solids. The solids are dissolved in water, dialyzed, and the active aminoacylase is recovered from the dialyzed solution. This method produces aminoacylase with high specific activity and requires fewer purification steps. The aminoacylase obtained can be utilized directly without subsequent purification to produce immobilized aminoacylase. Immobilization is achieved by covalent bonding of the aminoacylase to a partially hydrolyzed Akrilex P type acrylamide-N,N'-methylene-bis(arylamide) copolymer. The recovered aminoacylase can also undergo two chromatographic purification steps to yield a very pure product.
Career Highlights
Iren Huber is associated with Reanal Finomvegyszergyar, where he applies his expertise in biochemistry. His work has led to advancements in the efficiency of aminoacylase isolation, which is crucial for various biochemical applications.
Collaborations
Iren collaborates with notable colleagues, including Bela Szajani and Janosne Kiss, who contribute to his research and development efforts.
Conclusion
Iren Huber's innovative methods in aminoacylase isolation represent a significant advancement in biochemistry. His contributions are poised to enhance the efficiency of biochemical processes and applications.