Company Filing History:

9 out of 4,770

Merck + Co., Inc.

patents

1 out of 832,680

Other

patents

Years Active: 1994-2002

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10 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 6479672 - Diastereoselective preparation of Michael adducts (2002-11-12),

2. 6080876 - Process for making phenyl heterocycles useful as COX-2 inhibitors (2000-06-27),

3. 6046333 - Convergent process for the preparation of a growth hormone secretagogue (2000-04-04),

4. 6028196 - Process for the preparation of a growth hormone secretagogue (2000-02-22),

5. 5856498 - Method of preparing phosphodiesterase IV inhibitors (1999-01-05),

6. 5728838 - Method of preparing phosphodiesterase IV inhibitors (1998-03-17),

7. 5489685 - Method of synthesizing furo[2,3-b]pyridine carboxylic acid esters (1996-02-06),

8. 5426230 - Process for the preparation of 4-chloro-2-cyclopropylcarbonylaniline (1995-06-20),

9. 5380849 - Process for optically pure decahydroisoqiunolines (1995-01-10),

10. 5290941 - Facile condensation of methylbenzoxazoles with aromatic aldehydes (1994-03-01),

Title: Ioannis N Houpis: Innovator in Pharmaceutical Chemistry

Introduction

Ioannis N Houpis is a notable inventor based in Edison, NJ (US), recognized for his contributions to pharmaceutical chemistry. He holds a total of 10 patents, showcasing his innovative approach to solving complex chemical challenges.

Latest Patents

Among his latest patents, Houpis has developed a method for the diastereoselective preparation of Michael adducts. This process involves conducting Michael addition in the presence of a zinc-amine complex, resulting in products with high diastereomeric excess. Additionally, he has created a process for making phenyl heterocycles that are useful as COX-2 inhibitors, which are significant in the treatment of cyclooxygenase-2 mediated diseases.

Career Highlights

Throughout his career, Houpis has worked with prominent companies, including Merck & Company, Inc. His work has significantly impacted the field of medicinal chemistry, particularly in the development of new therapeutic agents.

Collaborations

Houpis has collaborated with notable colleagues such as Ralph P Volante and Audrey Molina, contributing to various innovative projects in the pharmaceutical sector.

Conclusion

Ioannis N Houpis stands out as a significant figure in the realm of pharmaceutical innovations. His patents and collaborations reflect his dedication to advancing medical science through chemistry.

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