Immanuel F Luescher

Title: Immanuel F. Luescher: Innovator in Reversible Protein Multimers

Introduction

Immanuel F. Luescher is a notable inventor based in Gollion, Switzerland. He has made significant contributions to the field of protein engineering, particularly in the development of reversible protein multimers. His work has implications for cancer research and immunology.

Latest Patents

Luescher holds three patents, with his latest focusing on reversible protein multimers and methods for their production and use. One of his key inventions involves reversible MHC protein multimers, which are designed to enhance the detection and isolation of specific T-cells or T-cell populations. These multimers can efficiently dissociate, minimizing the time of MHC binding to T-cell receptors, thereby reducing T-cell activation. This innovation allows for the identification of antigen-specific CD8+ T cells without inducing activation-dependent cell death, which is crucial for isolating rare T-cells that may have therapeutic value.

Career Highlights

Luescher is affiliated with the Ludwig Institute for Cancer Research Limited, where he continues to advance his research in protein multimers. His work is pivotal in developing methods that can be applied in various settings, including research, diagnostics, and therapy.

Collaborations

Some of his notable coworkers include Julien Schmidt and Philippe Guillaume, who have collaborated with him on various projects related to his patents.

Conclusion

Immanuel F. Luescher's innovative work in reversible protein multimers represents a significant advancement in the field of immunology and cancer research. His contributions are expected to have a lasting impact on the detection and treatment of diseases.