Ilse I Blumentals

Title: Ilse I Blumentals: Innovator in Thermostable Enzymes

Introduction

Ilse I Blumentals is a notable inventor based in Silver Spring, MD (US). She has made significant contributions to the field of biotechnology, particularly in the development of thermostable DNA polymerases and proteolytic enzymes. With a total of 3 patents, her work has implications for various applications in molecular biology and biochemistry.

Latest Patents

One of her latest patents involves a thermophilic DNA polymerase. This invention relates to a substantially pure thermostable DNA polymerase, which has a molecular weight of about 95 kilodaltons and is more thermostable than Taq DNA polymerase. The patent also covers the cloning and expression of the DNA polymerase in E. coli, as well as DNA molecules containing the cloned gene and host cells that express these genes.

Another significant patent focuses on proteolytic enzymes derived from hyperthermophilic bacteria. Cell-free extracts from Pyrococcus furiosus were found to exhibit unusually high levels of proteolytic activity, with minimal loss in activity even after prolonged incubation at high temperatures. The protease identified in this patent retains significant activity under various conditions, showcasing its potential for industrial applications.

Career Highlights

Ilse I Blumentals is affiliated with The Johns Hopkins University, where she continues her research and innovation in the field of biotechnology. Her work has garnered attention for its practical applications in scientific research and industry.

Collaborations

She has collaborated with notable colleagues, including Robert M Kelly and Anne K Robinson, who have contributed to her research endeavors.

Conclusion

Ilse I Blumentals stands out as an influential inventor in the realm of thermostable enzymes, with her patents paving the way for advancements in molecular biology. Her contributions continue to impact the scientific community and industry alike.