Ian H Holmes

Title: Innovations by Ian H Holmes

Introduction

Ian H Holmes is a notable inventor based in Berkeley, CA. He has made significant contributions to the field of gene therapy through his innovative work with adeno-associated viruses. His research focuses on enhancing the infectivity of these viruses for targeted gene delivery.

Latest Patents

Holmes holds a patent for "Adeno-associated virus variants and methods of use thereof." This patent describes recombinant adeno-associated virus (rAAV) virions that comprise a variant AAV capsid protein. The rAAV virions can exhibit greater infectivity of target cells, which is crucial for effective gene therapy. The patent also outlines methods for delivering gene products to target cells in individuals by administering the rAAV. Furthermore, it provides techniques for generating rAAV virions with variant AAV capsid proteins derived from ancestral AAV capsid protein amino acid sequences. Holmes has 1 patent to his name.

Career Highlights

Holmes is affiliated with the University of California, where he conducts his research. His work has been instrumental in advancing the understanding and application of gene therapy techniques.

Collaborations

Some of his notable coworkers include David Stephen Ojala and Jorge Santiago-Ortiz. Their collaborative efforts contribute to the innovative research being conducted at the University of California.

Conclusion

Ian H Holmes is a pioneering inventor whose work in adeno-associated viruses has the potential to revolutionize gene therapy. His contributions are significant in the ongoing quest to improve targeted gene delivery methods.