I Lawrence Greenfield

Title: I Lawrence Greenfield: Innovator in Nucleic Acid Polymerase Enzymes

Introduction

I Lawrence Greenfield is a notable inventor based in Pleasant Hill, CA (US). He has made significant contributions to the field of molecular biology, particularly in the development of thermostable nucleic acid polymerase enzymes. With a total of 5 patents, his work has had a profound impact on various applications in biotechnology and genetic research.

Latest Patents

Greenfield's latest patents include innovations such as a purified thermostable nucleic acid polymerase enzyme derived from the eubacterium Thermus species Z05. This enzyme exhibits DNA polymerase activity, reverse transcriptase activity, and optionally 5' to 3' exonuclease activity. The enzyme can be either native or recombinant and is designed for use in temperature-cycling chain reactions, where it amplifies nucleic acid sequences from existing templates.

Career Highlights

Throughout his career, Greenfield has worked with prominent companies in the biotechnology sector, including Roche Molecular Systems, Inc. and Hoffmann-La Roche Inc. His expertise in enzyme development has positioned him as a key figure in advancing molecular biology techniques.

Collaborations

Greenfield has collaborated with esteemed colleagues such as David H. Gelfand and Richard D. Abramson. These partnerships have further enhanced his contributions to the field and facilitated the development of innovative solutions in nucleic acid research.

Conclusion

I Lawrence Greenfield's work in the field of thermostable nucleic acid polymerase enzymes exemplifies the spirit of innovation in biotechnology. His patents and collaborations continue to influence advancements in molecular biology, showcasing the importance of his contributions to science.