This inventor holds 2 USPTO granted patents. Top assignee: Chong Kun Dang Corporation. Active years: 1999-2003.
Location History:
- Seoul, KR (1999)
- Ansan, KR (2003)
Company Filing History:
Years Active: 1999-2003
Title: Innovations of Inventor Hung Bae Chang
Introduction
Hung Bae Chang is a notable inventor based in Ansan, South Korea. He has made significant contributions to the field of biotechnology, particularly in the development of immunosuppressive agents. With a total of 2 patents to his name, his work has the potential to impact medical treatments significantly.
Latest Patents
Hung Bae Chang's latest patents include the invention of a novel Streptomyces sp. that produces tautomycetin, which possesses immunosuppressive and antibacterial activities. This invention relates to a process for preparing tautomycetin from the microorganism and an immunosuppressant pharmaceutical composition that includes tautomycetin as an active ingredient. The invention aims to suppress interleukin-2 production and CD69 and interleukin-2 receptor (IL-2R) expression on the cell surface, which is crucial in preventing graft rejection during organ transplantation. The research led to the isolation of a soil microorganism that produces a substance with antibiotic and immunosuppressive properties, identified as a novel Streptomyces sp. and tautomycetin. Furthermore, the inventor developed a method for large-scale manufacturing of tautomycetin from the culture of the microorganism, demonstrating its effectiveness in suppressing mouse mixed lymphocyte reaction (MLR) and IL-2 expression through a series of experiments.
Career Highlights
Hung Bae Chang is currently associated with Chong Kun Dang Corporation, where he continues to innovate in the field of pharmaceuticals. His work has garnered attention for its potential applications in medical treatments, particularly in immunology.
Collaborations
He has collaborated with notable colleagues, including Jung Woo Kim and Hyoung Sik Chun, to advance his research and development efforts.
Conclusion
Hung Bae Chang's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His work on tautomycetin and its applications in immunosuppression showcases the potential for innovative solutions in medical science.