Location History:
- Shanghai, CN (2021)
- Nanjing, CN (2020 - 2022)
Company Filing History:
3 out of 13 
3 out of 125 Years Active: 2020-2022
Title: Huilei Yu: Innovator in Chiral Sulfoxide Production
Introduction
Huilei Yu is a prominent inventor based in Nanjing, China, known for his significant contributions to the field of biocatalysis and pharmaceutical development. With a total of three patents to his name, he has made strides in the production of chiral sulfoxides, which are essential in the creation of various drugs.
Latest Patents
One of Huilei Yu's latest patents is titled "Monooxygenase and use in preparation of optically pure sulfoxide." This patent discloses a monooxygenase with an amino acid sequence obtained through mutation, which is advantageous for producing chiral sulfoxide-based drugs. The benefits of this invention include mild reaction conditions, environmental friendliness, high yield, and high optical purity of products. This monooxygenase shows great industrial application potential, particularly in the production of proton pump inhibitors for treating gastric ulcers.
Another notable patent is "Burkholderia and applications thereof," which involves a strain identified as ECU0712, with an accession number of CGMCC NO. 14464. This strain or its extract serves as a biocatalyst to oxidize thioether asymmetrically to chiral sulfoxide. The resulting product boasts high optical purity, a simple reaction system, a short preparation time for the catalyst, and a high yield.
Career Highlights
Huilei Yu has worked with notable organizations such as Jiangsu Aosaikang Pharmaceutical Co., Ltd. and East China University of Science and Technology. His experience in these institutions has contributed to his expertise in the field of biocatalysis and drug development.
Collaborations
Some of Huilei Yu's coworkers include Yan Mei Zhang and Jianhe Xu. Their collaborative efforts have likely enhanced the research and development of innovative solutions in their respective fields.
Conclusion
Huilei Yu's work in the development of chiral sulfoxides and biocatalysis demonstrates his commitment to advancing pharmaceutical science. His patents reflect a strong potential for industrial application, particularly in the production of essential medications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.