Huijun Zhou

Title: Huijun Zhou: Innovator in Tumor Diagnosis

Introduction

Huijun Zhou is a notable inventor based in Changsha, China. He has made significant contributions to the field of medical diagnostics, particularly in the early detection of tumors. His innovative work has led to the development of a unique multi-signal fluorescent probe.

Latest Patents

Huijun Zhou holds a patent for a "Multi-signal fluorescent probe for early diagnosis of tumors, and preparation and use thereof." This invention involves a method for preparing the multi-signal fluorescent probe, which includes several steps. The process begins with adding 2-methoxyphenothiazine and ethyl iodide into a mixture of dichloromethane (DCM) and acetonitrile, followed by a first reaction and post-treatment to obtain 10-ethyl-2-methoxy-10H-phenothiazine. The next step involves adding boron tribromide into the 10-ethyl-2-methoxy-10H-phenothiazine under an inert gas, followed by a second reaction under an ice bath and post-treatment to obtain 10-ethyl-10H-phenothiazin-2-ol. Finally, the 10-ethyl-10H-phenothiazin-2-ol is mixed with malonic acid, zinc chloride, and phosphorus oxychloride, followed by a third reaction and post-treatment to obtain the multi-signal fluorescent probe. This probe is also utilized in the detection of intracellular ONOO and NaS.

Career Highlights

Throughout his career, Huijun Zhou has worked at prominent institutions such as Hunan Cancer Hospital and Hunan Normal University. His work in these organizations has allowed him to focus on cancer research and innovative diagnostic methods.

Collaborations

Huijun Zhou has collaborated with notable colleagues, including Zhenyang Liu and Pan Chen, who have contributed to his research endeavors.

Conclusion

Huijun Zhou's innovative work in developing a multi-signal fluorescent probe represents a significant advancement in tumor diagnosis. His contributions to medical science continue to impact the field positively.