Company Filing History:
Years Active: 2021-2023
Title: Innovator Hui Li: Pioneering Advances in Gene Editing
Introduction
Hui Li, an accomplished inventor based in Apex, North Carolina, has made significant contributions in the field of biotechnology. With a portfolio of three patents, he is at the forefront of developing innovative engineered nucleases that hold promise for the treatment of various diseases, including cancer and hepatitis B.
Latest Patents
Hui Li's latest patents include:
1. **Optimized Engineered Nucleases for T Cell Receptor Alpha Constant Region Gene**: This invention focuses on engineered nucleases that recognize and cleave a specific recognition sequence within the first exon of the human T cell receptor alpha constant region gene. These engineered meganucleases exhibit enhanced specificity and efficiency, paving the way for creating genetically-modified cells for potential therapeutic use.
2. **Engineered Meganucleases for Hepatitis B Virus Genome**: This patent encompasses engineered nucleases designed to recognize and cleave sequences within the Hepatitis B virus genome. Similar to his previous work, these meganucleases showcase improved characteristics compared to first-generation versions, and they aim to provide new avenues for treating HBV infections and related diseases, such as hepatocellular carcinoma.
Career Highlights
Hui Li is currently affiliated with Precision Biosciences, Inc., where he continues to develop cutting-edge biotechnological solutions. His work in engineered nucleases positions him as a leader in the field, contributing to advancements in gene editing and therapeutic applications.
Collaborations
Throughout his career, Hui has collaborated with notable colleagues such as James Jefferson Smith and Janel Lape. These partnerships further enhance the innovative potential of his projects, fostering a collaborative environment focused on breakthrough discoveries in biotechnology.
Conclusion
Hui Li's innovative approach to developing engineered nucleases exemplifies the transformative power of biotechnology in medicine. With his ongoing contributions and collaborations, he is undoubtedly a key player in shaping the future of genetic engineering and therapeutic interventions.