This inventor holds 1 USPTO granted patent. Top assignee: Institute of Nuclear Energy Research. Active years: 2002.
Company Filing History:
Years Active: 2002
Title: Innovator Hui-Lan Wu: Advancements in Peptide Synthesis
Introduction
Hui-Lan Wu, an accomplished inventor based in Kaohsiung, Taiwan, has made significant contributions to the field of peptide synthesis. With one patented invention under his name, Wu focuses on innovations that enhance the preparation processes of important compounds used in various medical applications.
Latest Patents
Wu's notable patent, titled "Process for preparing octreotide and derivatives thereof," outlines a unique method for synthesizing octreotide, a synthetic form of the naturally occurring somatostatin. The process begins with the coupling of Thr(ol)(tBu)-2-chlorotrityl resin with various amino acids to create a straight peptide-resin. This resin can produce essential peptide structures, including D-Phe-Cys(Trt)-Phe-D-Trp(Boc)-Lys(Boc)-Thr(tBu)-Cys(Trt)-Thr(ol)(tBu)-2-chlorotrityl resin and D-Phe-Cys(Trt)-Tyr(tBu)-D-Trp(Boc)-Lys(Boc)-Thr(tBu)-Cys(Trt)-Thr(ol)(tBu)-2-chlorotrityl resin. The innovative method concludes with the cleavage of the peptide from the resin using a strong acid solution, followed by a reaction with charcoal that yields disulfide-containing peptide, showcasing Wu's expertise in peptide chemistry.
Career Highlights
Hui-Lan Wu is affiliated with the Institute of Nuclear Energy Research, where he actively conducts research and development in peptide synthesis. His work has implications for pharmaceuticals, particularly in therapies requiring peptide-based treatments. Wu's commitment to advancing scientific knowledge in this specialized field places him among noteworthy inventors in peptide chemistry.
Collaborations
Throughout his career, Wu has collaborated closely with talented colleagues, including Yao-Tsung Hsieh and Shiang-Rong Chang. Their collective efforts in research and innovation have significantly furthered advancements in peptide synthesis, demonstrating the power of teamwork in achieving scientific breakthroughs.
Conclusion
As an inventor, Hui-Lan Wu continues to pave the way for innovations in peptide synthesis. His patented process for preparing octreotide reflects a blend of creativity and scientific rigor that can potentially impact medical science. Wu's inventive spirit, combined with his collaborative efforts with peers, exemplifies the importance of innovation in the pursuit of better healthcare solutions.