Yardley, PA, United States of America

Hugh P Schieren



Average Co-Inventor Count = 9.0

ph-index = 4

Forward Citations = 322(Granted Patents)


Company Filing History:


Years Active: 1989-1999

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4 patents (USPTO):Explore Patents

Title: Hugh P. Schieren: Innovator in Liposome Technology

Introduction

Hugh P. Schieren is a notable inventor based in Yardley, PA (US), recognized for his contributions to the field of liposome technology. With a total of four patents to his name, Schieren has made significant advancements in methods related to the dehydration, storage, and rehydration of liposomes.

Latest Patents

Schieren's latest patents focus on innovative methods for dehydrating liposomes. One of his key inventions involves preparing dehydrated liposomes by drying liposome preparations under reduced pressure in the presence of protective sugars such as trehalose and sucrose. This method ensures that the protective sugars are present on both the inside and outside surfaces of the liposome membranes. Additionally, he has developed techniques for encapsulating ionizable agents in liposomes, which can be utilized for drug delivery. These advancements allow for the creation of concentration gradients that generate transmembrane potentials, facilitating the loading of charged materials into the liposomes.

Career Highlights

Throughout his career, Schieren has worked with prominent companies in the field, including The Liposome Company, Inc. and The Liposome Company, Inc. His work has significantly impacted the development of liposome-based technologies, enhancing their applications in pharmaceuticals and biotechnology.

Collaborations

Some of Schieren's notable coworkers include Andrew S. Janoff and Pieter Rutter Cullis. Their collaborative efforts have contributed to the advancement of liposome research and technology.

Conclusion

Hugh P. Schieren's innovative work in liposome technology has paved the way for new methods in drug delivery and storage. His patents reflect a deep understanding of the complexities involved in liposome preparation and application.

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