Location History:
- PingTung, TW (2009 - 2013)
- Pingtung County, TW (2010 - 2016)
- Neipu, TW (2011 - 2023)
Company Filing History:
8 out of 83 
1 out of 1 Years Active: 2009-2025
Title: Hso-Chi Chaung: Innovator in Immunology and Vaccine Development
Introduction
Hso-Chi Chaung is a prominent inventor based in Pingtung County, Taiwan. He has made significant contributions to the field of immunology, particularly in the development of vaccines and methods for evaluating immune responses. With a total of nine patents to his name, Chaung's work is at the forefront of scientific innovation.
Latest Patents
Among his latest patents is a recombinant antigen and method of making the same, which focuses on the porcine reproductive and respiratory syndrome virus (PRRSV). This invention includes a chimeric protein of PRRSV dual structural proteins and T-cell epitope. The polynucleotide encodes an amino acid sequence of the recombinant antigen, which can be expressed in a eukaryotic system for mass production and purification. Additionally, an immunogenic composition that includes this recombinant antigen promotes pro-inflammatory M1-phenotype polarization of porcine alveolar macrophages, reduces receptor CD163 expression, and activates T helper immune responses, making it a potential vaccine against PRRSV.
Another notable patent is the in vitro immune synapse system and method for evaluating immune response. This system comprises antigen-presenting cells and specific T cell subtypes isolated from the same individual of pigs. By co-culturing a test sample in this system, researchers can determine its immunogenicity and immunostimulatory properties, potentially reducing the need for certain animal experiments.
Career Highlights
Hso-Chi Chaung has worked with esteemed institutions such as the National Pingtung University of Science & Technology and Wholesome Life Science Co., Ltd. His career reflects a commitment to advancing scientific knowledge and practical applications in immunology.
Collaborations
Chaung has collaborated with notable colleagues, including Mei-Li Wu and Wen-Bin Chung. These partnerships have contributed to the success of his research and innovations.
Conclusion
Hso-Chi Chaung's work in immunology and vaccine development showcases his dedication to improving health outcomes through innovative research. His patents reflect a significant impact on the field, particularly in combating viral diseases in livestock.