Hsiu-Fen Ko

Title: Hsiu-Fen Ko: Innovator in Antibody Technology

Introduction

Hsiu-Fen Ko is a prominent inventor based in Kaohsiung, Taiwan. She has made significant contributions to the field of biotechnology, particularly in the development of innovative antibody technologies. Her work focuses on creating solutions that enhance the efficacy of protein drugs.

Latest Patents

Hsiu-Fen Ko holds a patent for an "Antibody locker for the inactivation of protein drug." This invention discloses a hinge antibody capable of being selectively activated in target cells or tissues to treat specific conditions. The hinge antibody comprises a functional antibody, two inhibitory domains, and four cleavable linkers. The functional antibody is designed to treat conditions in an activated state, featuring two light chains and two heavy chains. Each inhibitory domain includes a hinge domain of an immunoglobulin and consists of two peptide arms. The cleavable linkers connect the peptide arms of the inhibitory domains to the N-terminal of the light and heavy chains of the functional antibody, allowing for targeted therapeutic applications.

Career Highlights

Throughout her career, Hsiu-Fen Ko has worked with notable institutions, including Kaohsiung Medical University and DCB-USA LLC. Her experience in these organizations has allowed her to advance her research and contribute to the field of antibody technology.

Collaborations

Hsiu-Fen Ko has collaborated with esteemed colleagues such as Tian-Lu Cheng and Chih-Hung Chuang. These partnerships have fostered innovation and have been instrumental in her research endeavors.

Conclusion

Hsiu-Fen Ko's contributions to antibody technology exemplify her dedication to advancing medical science. Her innovative patent and collaborative efforts highlight her role as a leading inventor in the biotechnology field.