Location History:
- Derwood, MD (US) (1995 - 1997)
- Bethesda, MD (US) (1996 - 1998)
Company Filing History:
3 out of 4 
3 out of 18 
1 out of 1 Years Active: 1995-1998
Title: The Innovative Contributions of Howard C. Krivan
Introduction
Howard C. Krivan is a prominent inventor based in Bethesda, MD, known for his significant contributions to immunology and vaccine development. With a total of 7 patents to his name, his work focuses on enhancing human and mammalian health through innovative vaccine technologies.
Latest Patents
Among Krivan's notable patents is the "Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae." This invention discloses immunogenic polysaccharide-H. influenzae adhesin protein conjugates, along with a purified H. influenzae adhesin protein and related materials. These conjugates, comprising synthetic oligosaccharides coupled with the H. influenzae adhesin protein, aim to provide a new method of protecting humans and other mammals against H. influenzae infections.
Additionally, he has developed a patent focused on "DNA encoding a novel Haemophilus influenzae protein." This patent reveals an immunogenic Haemophilus influenzae outer membrane protein of 49 kDa, along with a mature outer membrane protein of 47 kDa. It includes the necessary DNA and vectors for producing these proteins, highlighting methods applicable in vaccine production against H. influenzae.
Career Highlights
Throughout his career, Howard C. Krivan has made impactful strides at notable companies such as Microcarb, Inc. and Antex Biologics, Inc. His innovative mindset has greatly influenced the advancement of vaccine-related technologies, demonstrating his commitment to improving public health.
Collaborations
Krivan has collaborated with esteemed colleagues, including James E. Samuel and A. Lennart Blomberg. These collaborations have fostered an environment of creativity and innovation, leading to groundbreaking developments in his field.
Conclusion
Howard C. Krivan's work as an inventor continues to advance medical science, particularly in the realm of vaccine development. With his significant patents and collaborative efforts, he remains a crucial figure in the pursuit of better health solutions for humanity.