Hortense W Dodo

Title: Innovations of Hortense W Dodo in Allergen-Free Peanut Seeds

Introduction

Hortense W Dodo is a notable inventor based in Huntsville, AL (US). He has made significant contributions to the field of biotechnology, particularly in the development of allergen-free transgenic peanut seeds. With a total of 2 patents, his work focuses on enhancing food safety and reducing allergic reactions associated with peanut consumption.

Latest Patents

Dodo's latest patents involve the down-regulation and silencing of allergen genes in transgenic peanut seeds. This innovative approach utilizes recombinant methods to produce allergen-free peanut seeds. The process includes transforming peanut plants with multiple copies of allergen genes or fragments to suppress gene expression and allergen protein production. Additionally, peanut plants are modified with antisense genes to further reduce allergen levels. The transgenes are regulated by the 35S promoter or the promoter of the Ara h2 gene, facilitating the production of various RNA types that inhibit allergen protein synthesis. His research has led to the isolation and sequencing of a full-length genomic clone for allergen Ara h2, revealing critical genetic information that aids in the screening of peanut genomic libraries.

Career Highlights

Throughout his career, Dodo has focused on innovative solutions to address food allergies, particularly in peanuts. His research has the potential to significantly impact public health by providing safer food options for individuals with peanut allergies.

Collaborations

Dodo has collaborated with esteemed colleagues such as Charles Joel Arntzen and Olga Martha Viquez, contributing to the advancement of research in allergen reduction.

Conclusion

Hortense W Dodo's work in developing allergen-free peanut seeds represents a significant advancement in biotechnology. His innovative approaches and collaborations continue to pave the way for safer food products and improved health outcomes for those with food allergies.