Horst Thurow

Title: Horst Thurow: Innovator in Protein Technology

Introduction

Horst Thurow is a notable inventor based in Kelkheim, Germany. He has made significant contributions to the field of protein technology, holding a total of 4 patents. His work focuses on processes that enhance the stability and drying of protein crystals, which are crucial in various biotechnological applications.

Latest Patents

One of Thurow's latest patents is a process for drying protein crystals. This invention relates to a method that begins with an aqueous protein crystal suspension. The process involves drying the protein crystal suspension in a centrifugal dryer, where the filtered protein crystals are brought into contact with a drying medium. This medium consists of a mixture of water and a nonaqueous solvent that is miscible with water in any ratio and has a lower vapor pressure than water. The use of a drying gas moistened with water is also advantageous in this process. Additionally, the protein crystal suspension is converted into a fluidized bed for effective drying.

Another significant patent involves aqueous protein solutions that are stable to denaturation. This invention discloses a method for preventing the denaturation of proteins, such as insulin, in aqueous solutions at interfaces. This is achieved by adding a surface-active substance that comprises a chain of alternating weakly hydrophobic and weakly hydrophilic zones. The patent also covers methods for purifying proteins contained in such solutions and treating surfaces with the surface-active material to prevent protein denaturation.

Career Highlights

Throughout his career, Horst Thurow has worked with prominent companies in the pharmaceutical and biotechnology sectors. He has been associated with Hoechst Aktiengesellschaft and Aventis Pharma Deutschland, GmbH. His experience in these organizations has contributed to his expertise in protein technology and innovation.

Collaborations

Thurow has collaborated with notable colleagues, including Rolf Deusser and Peter Kraemer. These partnerships have likely enriched his research and development efforts in the field of protein technology.

Conclusion

Horst Thurow's innovative work in protein technology has led to significant advancements in the stability and processing of proteins. His patents reflect a deep understanding of the complexities involved in protein handling and processing, making him a valuable contributor to the field.