Location History:
- Longueuil, CA (1997)
- Lonqnenil, CA (1999)
Company Filing History:
Years Active: 1997-1999
Title: Innovations by Hongsheng Su: Pioneering Advances in Heparinase Research
Introduction: Hongsheng Su, an accomplished inventor based in Longueuil, Canada, has contributed significantly to the field of biotechnology with his innovative research. With a total of two patents to his name, he has made strides in the understanding and application of enzymes involved in the degradation of heparin and heparan sulfate.
Latest Patents: Hongsheng Su's latest patents focus on nucleic acid sequences and expression systems for heparinase II. These inventions describe the isolation and sequencing of genes from Flavobacterium heparinum that encode crucial enzymes like heparinase II and heparinase III (EC 4.2.2.8). Furthermore, his patents outline a method for expressing these heparinases using a modified ribosome binding region derived from glycosaminoglycan lyase gene promoters of F. heparinum. A multi-step protein purification method is also featured, which includes cell disruption, cation exchange chromatography, affinity chromatography, and hydroxylapatite chromatography. Additionally, the patents detail the creation of antibodies targeting post-translational modification moieties specific to F. heparinum proteins, as well as methods to obtain antibodies that are specific to the amino acid sequences of heparinases I, II, and III.
Career Highlights: As part of Ibex Technologies Ltd., Hongsheng Su has been at the forefront of biotechnological advancements. His expertise and dedication not only contribute to his organization's goals but also push the boundaries of enzyme research in therapeutic applications.
Collaborations: Throughout his career, Hongsheng has collaborated with notable professionals such as Francoise Blain and Clark Bennett. These partnerships emphasize the importance of teamwork in driving innovative research and developing new technologies that benefit the scientific community.
Conclusion: Hongsheng Su's contributions to enzyme research through his patented inventions highlight the critical role of innovation in biotechnology. His work with heparinase enzymes represents significant advancements in the field, demonstrating how dedicated inventors can change the landscape of scientific research for better medical applications.