Hongliang Liu

Title: Innovations and Contributions of Inventor Hongliang Liu

Introduction

Hongliang Liu is a prominent inventor based in Beijing, China. He has made significant contributions to the fields of materials science and pharmaceuticals. With a total of four patents to his name, Liu's work focuses on improving high-temperature plasticity in materials and developing methods for drug synthesis.

Latest Patents

One of Liu's latest patents is a vacuum solution and aging treatment process for improving the high-temperature plasticity of GH4738 rings. This innovative process involves heating a GH4738 ring to temperatures between 1020°C and 1030°C in a vacuum environment, followed by nitrogen injection. The ring undergoes aging treatment at temperatures ranging from 740°C to 750°C, and is then air-cooled. This method ensures a uniform distribution of intragranular γ' precipitates and intergranular MC carbides, resulting in significant improvements in elongation and area reduction of the alloy ring after heat treatment. The elongation and area reduction at 540°C are 30% and 34% respectively, which are 25% and 36% higher than before process optimization. At 760°C, the improvements are even more pronounced, with elongation and area reduction reaching 49% and 70%, respectively.

Another notable patent by Liu is a method for preparing lornoxicam, a drug used for pain relief. This method utilizes 6-chloro-4-hydroxy-2-methyl-2-H-thieno[2,3-e]-1,2-thiazine methyl carboxylate-1,1-dioxide and 2-aminopyridine as raw materials, with xylene as a solvent. The process involves mixing the raw materials and solvent, adding a stabilizer, and conducting ammonolysis. The resulting reactant is cooled, and the solvent is removed through vacuum concentration. An organic solvent is then added, and the mixture is filtered to obtain crude lornoxicam, which is subsequently refined to yield the final product. The use of p-toluenesulfonic acid as a stabilizer enhances the reaction efficiency and product quality.

Career Highlights

Liu has worked with notable companies such as Beijing Choice Electronic Technology Co., Ltd. and Beijing Jincheng Taier Pharmaceutical Co., Ltd. His experience in these organizations has contributed to his expertise in both