Location History:
- New York, NY (US) (1999)
- Shrewsbury, MA (US) (2001 - 2004)
- Worcester, MA (US) (2001 - 2006)
Company Filing History:
4 out of 1,697 
1 out of 7 
1 out of 832,912 Years Active: 1999-2006
Title: Innovator Hongkui Deng: Pioneering Research in HIV Therapeutics
Introduction: Hongkui Deng is a renowned inventor based in Worcester, MA, known for his significant contributions to the field of HIV research. With a portfolio of 5 patents, his innovations are focused on identifying and developing therapeutic agents that target HIV entry into host cells.
Latest Patents: Among his latest patents are critical inventions related to methods of identifying G-coupled receptors associated with macrophage-trophic HIV. His research has revealed that the principal cofactor for HIV-1 entry is CC-CKR5, a receptor that interacts with specific chemokines. Additionally, Deng has developed new translocation promoting agents named Bonzo and BOB, providing both the amino acid and DNA sequences for the receptor protein Bonzo. These inventions also include methods to identify agents that modulate Bonzo's expression and function, potentially offering new avenues for treating inflammation and enhancing immune responses.
Career Highlights: Hongkui Deng has held prominent positions at prestigious institutions, notably at New York University and the Aaron Diamond AIDS Research Center. His work has not only advanced the scientific understanding of HIV but has also paved the way for developing innovative therapeutic strategies against the virus.
Collaborations: Throughout his illustrious career, Deng has worked with notable scientists such as Dan R. Littman and Wilfried Ellmeier. These collaborations have further enhanced the impact of his research and contributed to the collective effort in combating HIV.
Conclusion: With his impressive portfolio of patents and collaborations, Hongkui Deng stands as a leading figure in the field of HIV research. His dedication to developing therapeutic solutions exemplifies the power of innovation in the fight against devastating diseases. Through his ongoing efforts, the scientific community remains hopeful for new advances in HIV treatment and prevention.