Hongji Ren

Title: The Innovative Contributions of Hongji Ren in Optical Systems

Introduction

Hongji Ren, an esteemed inventor based in San Diego, California, has made significant strides in the field of optical systems with a remarkable portfolio of 20 patents. His inventions primarily focus on improving microscopy techniques and dynamic imaging methods, reflecting his commitment to enhancing the capabilities of scientific analysis.

Latest Patents

Among his latest patents is an "Apparatus and method of estimating values from images." This innovative method generates a distortion model for structured illumination microscopy (SIM) optical systems. It involves moving a sliding window in relation to multiple images, defining an array of sub-tiles, which represent segments of the corresponding image. The technique focuses on estimating key parameters for each sub-tile, including modulation, angle, spacing, phase offset, and phase deviation. Through these estimations and a full width at half maximum (FWHM) value, the methodology allows for a comprehensive distortion model to be built, enabling the generation of a two-dimensional image that highlights distortions occurring within the optical system.

Another notable invention is the "Dynamic autofocus method and system for assay imager." This patent details a method for scanning a microarray that includes features with various target molecules. The optical scanner dynamically controls the focus setting in real-time, adjusting to minimize focus errors while acquiring optical signals at different focus levels. This innovative approach facilitates the identification of diverse target molecules through the analysis of optical signals garnered under varying degrees of focus.

Career Highlights

Hongji Ren has collaborated with prominent companies in the biotechnology field, notably Illumina Corporation and Illumina Cambridge Limited. His work at these institutions underscores his pivotal role in advancing optical technologies and their applications in molecular analysis.

Collaborations

Throughout his career, Hongji has worked alongside distinguished colleagues such as Robert Ezra Langlois and Wayne N George. Collaboration with these professionals has undoubtedly contributed to the ingenuity and success of his patented innovations.

Conclusion

Hongji Ren continues to pave the way in optical system advancements with his inventive spirit and prolific patent contributions. His work not only contributes to scientific progress but also enhances the potential capabilities of microscopy and imaging technologies, ensuring a lasting impact on the field.