Company Filing History:
3 out of 1,087 
1 out of 81 Years Active: 2013-2025
Title: Innovations of Inventor Hong Yuan
Introduction
Hong Yuan is a notable inventor based in Hangzhou, China. He has made significant contributions to the field of biomedical engineering, particularly in the development of blood-brain barrier permeability regulators. With a total of 4 patents to his name, his work has the potential to impact therapeutic strategies for various neurological conditions.
Latest Patents
One of Hong Yuan's latest patents is focused on the use of Axitinib and its analogs in preparing a blood-brain barrier permeability regulator. This invention aims to reduce blood-brain barrier permeability and promote recovery from pathologically impaired states. The mechanism involves inhibiting the vascular endothelial cell growth factor signaling pathway, which helps maintain the integrity of tight junction proteins like Claudin-5 and Occludin.
Another significant patent involves the use of SC79 or its analogs in the preparation of a similar permeability regulator. This invention enhances the efficiency of brain-targeting drug delivery systems, particularly those modified with Angiopep-2. By activating the Claudin-5 and Occludin signaling pathways, this regulator increases blood-brain barrier permeability, thereby improving therapeutic efficacy.
Career Highlights
Hong Yuan has worked with prominent institutions such as Zhejiang University and Zhejiang Sanhua Automotive Components Co., Ltd. His experience in these organizations has contributed to his innovative research and development efforts in the biomedical field.
Collaborations
He has collaborated with notable colleagues, including Fuqiang Hu and Lijuan Wen, to advance his research initiatives. Their combined expertise has fostered a productive environment for innovation.
Conclusion
In summary, Hong Yuan is a distinguished inventor whose work on blood-brain barrier permeability regulators holds promise for enhancing drug delivery systems in treating neurological diseases. His contributions to the field are noteworthy and continue to pave the way for future innovations.
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