Company Filing History:
Years Active: 2019-2025
Title: The Innovator Behind Groundbreaking Antibody Therapies: Hong Wan
Introduction
Hong Wan is an accomplished inventor based in Foster City, California, whose innovative work has significantly contributed to the field of cancer treatment. With a remarkable portfolio of 12 patents, Wan is known for his advancements in antibody therapies that target specific proteins related to tumor progression.
Latest Patents
Among his latest inventions is a patent for antibodies against signal-regulatory protein alpha and methods of use. This patent details isolated antibodies that bind to various extracellular domains of human and non-human SIRP-α polypeptides. These antibodies play a crucial role in blocking or modulating interactions between SIRP-α and CD47 polypeptides, which could potentially influence tumor behavior.
Another notable patent focuses on combination therapies for treating hematological cancers, such as myelodysplastic syndrome. This innovation involves administering a unique polypeptide that combines a SIRPα D1 domain variant with a hypomethylating agent like azacitidine, along with related kits designed for practical application in clinical settings.
Career Highlights
Hong Wan's professional journey is marked by his association with Alx Oncology Inc., where he continues to refine and develop his groundbreaking inventions. His contributions to the field demonstrate a profound understanding of oncology and the therapeutic potential of targeted antibody therapies.
Collaborations
Throughout his career, Wan has collaborated with notable colleagues, including Jaume Pons and Bang Janet Sim. These collaborations have fostered an environment of innovation and have significantly enhanced the research efforts aimed at developing effective cancer therapies.
Conclusion
Hong Wan stands out not only as a prolific inventor but also as a leading figure in the realm of antibody research and development. His dedication to advancing cancer treatment through innovative applications of biotechnology reflects the vital role inventors play in shaping the future of medicine. As his work continues to evolve, it promises to bring hope and healing to patients facing challenging health battles.